There is more than one place called San Francisco, the Spanish name for Saint Francis. São Francisco is the Portuguese equivalent:
- São Francisco do Sul (San Francisco of the South) is the oldest city in Santa Catarina and the third oldest in Brazil. Situated on the island of São Francisco, it lies just west of Joinville and 200km north of Florinopolis.
- San Francisco is a seaside village in Nayarit, on the Pacific Coast of Mexico. It is a very tranquil place with no big businesses.
- San Francisco (Camotes Islands) — a town on the Camotes Islands
- St Francis Bay (Afrikaans: St Francisbaai) is a holiday town in Sarah Baartman District Municipality in the Eastern Cape province of South Africa, roughly one hour’s drive from Gqeberha.
- San Francisco — a consolidated city and county in northern California, in the western United States. It the largest city in northern California.
- St Francis (South Dakota) - a town on the Rosebud Indian Reservation in South Dakota.
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